Form & Quantity: Oral - 100 tablets per pack
Metabolic pathway: Hepatic
Oxymetholone: History, Chemistry And Pharmacology
Oxymetholone has gained so much notoriety for its potency and rapid-acting effect in bodybuilding, athletic, and recreational circles, that it is often used as what’s known as a “Kickstarter.” This means that it is used to rapidly increase the rate at which results are seen from the use of a set of anabolics. This is done because normally other anabolics are much more gradual in delivering results.
Structurally, it’s a form of Dihydrotestosterone, or DHT, with some chemical alterations made in the form of an added 2-hydroxy methylene chemical group, and a methyl group added to the 17th carbon point at the alpha position. This is what gives it its potent and rapid acting nature. However, it also makes it an incredibly stable chemical, which presents its own problems that are discussed in the sections below.
For now though, it is important to understand that Oxymetholone was originally used as a strong treatment for people with muscle wasting illnesses like HIV or cancer. However, its powerful anabolic properties meant that it soon made its way into the program of bodybuilders or athletes looking to get a competitive edge in their respective sports.
The way it acts in the body is similar, regardless of the individual. It would act to bind to androgen receptors at certain cells in the body and cause a change of signaling in these cells. This causes a sharp and large rise in protein manufacturing and a concurrent reduction in protein breakdown. Meanwhile, a high degree of nitrogen retention and red blood cell production occurs. This all leads to the coveted benefits, and some drawbacks, discussed below.
Dosing And Use
While the central effects and metabolization of Oxymetholone doesn’t change substantially from person to person, the dosing would differ based on a number of factors. These would include whether its use is for recreational, competitive or medical purposes, the user’s gender, and the user’s previous experience with anabolics.
In general, a commonly reported dose for males would stand at 50 all the way up to 300 milligrams weekly, administered into daily dosages. Females are recommended to stay away from it, due to its powerful nature, and therefore, the irreversible side effects it could exert on them.
Some individuals have reported that, instead of simply starting at a higher dose than 50 milligrams and maintaining a stagnant dosing practice, they have tried starting their dose at 50 milligrams and gradually increasing it by a single tablet (50 milligrams) either per day or per week, until they reach their goal dosage, for a reportedly more tolerable and efficient period of use.
Naturally, beginner users would normally be advised to adhere to the more conservative practices, as they will likely be more sensitive to the effects of the drug, both positive and negative.
As indicated in the first section, Oxymetholone is rarely used alone. It is most commonly combined with other products, in order to augment its results for the user.
The most common programs in which Oxymetholone is included is those where the goal is rapid and large, if inefficient, accruals of lean mass, strength, and power. And even at this, it is normally used at the start of these programs rather than introduced in the middle or at the end. These periods of use would normally last for only 4 to 6 weeks.
Results: The Positive And The Negative
As mentioned when talking about its chemical structure, the stable and potent nature of Oxymetholone acts as a double-edged sword. It can provide very fast and powerful benefits, but also some significant side effects. To give you a full picture of how its use may affect someone, we’ll look at both below.
The benefits of Oxymetholone include:
- Rapid and large increases in lean mass
- Large increases in strength and power output capacity
- A rise in work capacity
- Quicker and greater recovery from strenuous bouts of physical activity
- Decreased risk from injury
Adverse effects possible with the use of Oxymetholone can involve:
- Cardiovascular issues, including: A rise in blood pressure, increases in LDL cholesterol, reduced arterial wall flexibility, and an increased heart size.
- Hepatic strain with use, which may lead to damage if excessive amounts or periods of use are carried out.
- Androgenic-related issues, including: bouts of oily skin and acne, faster balding in people who are genetically predisposed to it, and the development of male characteristics in women, known as virilization.
- A suppression of endogenous testosterone manufacturing, which will persist even after use has ceased, which can lead to deficiency related problems if exogenous testosterone is not used to compensate for it.
- Bloating and the potential development of gynecomastia.
It should be noted that some of the above issues can be managed through, for example, following a heart-healthy diet and doing cardiovascular exercise in the first case, managing dose and duration for the second, utilizing a 5-alpha-reductase inhibitor in the third case, and carrying out a high-quality Post Cycle Therapy program after its use for the fourth instance. Finally, using a SERM may help manage some of the bloating too.
Warning And Precautions If Purchasing
Due to the immense popularity of this drug for athletic and recreational populations, there have been reported cases of counterfeit or contaminated products in circulation. This has included a fear of higher estrogen levels, which shouldn’t occur with Oxymetholone, and is likely a problem associated with contaminated products. This is why careful research should be done on the reputation of your vendor before purchasing. This can be done by checking reviews of previous buyers or independent review boards. Excessively cheap products can also sometimes be a big red flag when looking for high-quality products.
|Package||100 tablets (50 mg/tablet)|